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    <title>Peak detection - Deconvolution - Noise amplitude</title>
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<h1>Chromatogram deconvolution</h1>

<h2>Noise amplitude</h2>

<p>
    This method is suitable for chromatograms with significant background noise of varying intensities. It works in a
    similar way to the Baseline cut-off method, but sets the baseline level individually for each chromatogram,
    depending on the amplitude of signal noise.
</p>

<p>
    The baseline level is calculated as follows:
</p>
<ol>
    <li>The intensity range of the chromatogram is divided into bins of the user-specified size (the <em>Noise
        amplitude</em> parameter)
    </li>
    <li>The bin with the highest number of data points is found. This bin represents the intensity level of the noise
        signal.
    </li>
    <li>The baseline level is set to the intensity of the bin with the most data points</li>
</ol>

<p>
    <img src="noiseAnalysis1.jpg" alt="Noise analysis example">
    <img src="noiseAnalysis2.jpg" alt="Noise analysis example (zoomed)">
</p>

<h4>Method parameters</h4>

<dl>
    <dt>Min peak height</dt>
    <dd>Minimum acceptable height (intensity) for a chromatographic peak</dd>
    <dt>Peak duration range</dt>
    <dd>Range of acceptable peak durations</dd>
    <dt>Amplitude of noise</dt>
    <dd>This value is the intensity amplitude of the signal in the noise region</dd>
</dl>

<p>
    <img src="noise_amplitude.png" alt="Noise amplitude example">
</p>

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